IKBKAP

Aliases 
DKFZp781H1425, DYS, ELP1, FD, FLJ12497, IKAP, IKI3, TOT1
Chromosomal Locations 
9q31

The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling.

This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex.

Mutations in this gene have been associated with familial dysautonomia.

Description 
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein IKK complex-associated protein elongator complex protein 1 ikappaB kinase complex-associated protein p150
Tests 
Familial Dysautonomia